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The precise mechanisms of action and individual contributions of these components are unclear

Impaired lymphatic drainage of the arterial wall results in intimal lipid accumulation and atherosclerosis

Two studies in male Wistar rats that received LDX orally for 7 days demonstrated that LDX decreased antioxidant enzymes, such as catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD), revealing a potential mechanism of action related to oxidative stress [61, 62]

TNF- induces adipocytes to release free fatty acids, which in turn bind to Toll-like receptors on macrophages and adipocytes, further activating inflammatory signaling pathways and promoting the release of inflammatory factors (164)

Effects of tirzepatide versus insulin glargine on cystatin c-based kidney function: a SURPASS-4 post hoc analysis

It could also be used to help to assist in regenerating other antioxidants such as vitamin C and vitamin E once they have performed their function within a cell