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These studies suggested that abnormal ferritin overexpression, aggregation and consequent proteostasis could be the primary cause of neurodegeneration, while the impairment of iron metabolism might occur as a secondary event [101, 102]

(3) Vesicular displacement: Tyramine is transported into synaptic vesicles through vesicular monoamine transporter 2 (VMAT2), displacing norepinephrine (NE) from vesicular storage sites into the cytoplasm

Direct stimulation of NADP + synthesis through Akt-mediated phosphorylation of NAD kinase

Heme oxygenase-1 (HO-1) HO-1 is a crucial enzyme involved in the catabolism of heme, which has garnered significant attention in recent years due to its role in the regulation of ferroptosis

Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signalling in HER2-overexpressing SKBR3 breast cancer cells

C., Cheong, Y