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Reduced susceptibility of a sub-isolate from KCW remained through at least six lifecycle passages which demonsrates the traits heritability, despite the absence of drug pressure

Xu X, Liu S, Liu H, Ru K, Jia Y, Wu Z, et al

doi: 10.2105/AJPH.2014.302348

If you have high homocysteine with this genotype, you could focus on increasing dietary folate or supplementing with methylfolate

Other possible medication interactions include disruption of estrogen therapy, slowed glucuronidated drug clearance, and accelerated absorption of Pglycoprotein substrates

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