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It also shows highly conserved subcellular localisation, being predicted to localise to the ER in 13 of the 14 metazoans that encode it (Fig
To further support the impact of CBS on replenishing GSH levels under cystine-restricted conditions, we expressed a codon-optimized CBS (CBS OPT ), which is resistant to the designed sgRNA (Fig
, The space that is formed between them is rapidly filled with a loose extracellular matrix, the primary vitreous body, that is secreted by the cells of inner layer of the optic cup ( Fig
10.1111/apha.13216 23 BaekY.WooT
Ouyang X, Liu Y, Zheng K, Pang Z, Peng S
