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Clinical trials show no serious side effects

Increased levels of LPO together with decreased levels of serum ceruloplasmin and transferrin suggest that children with autism are under increased oxidative stress, likely due to abnormal metabolism of pro-oxidant metal ions and/or decreased antioxidant proteins

Compared with the CaOx group, treatment with the agonist, erastin, increased the relative expression of ACSL4, TF and TRC, and reduced that of XCT and GPX4

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Pubmed Central PMCID: 1762099

The Alzheimer's Association clinical practice guideline for the diagnostic evaluation, testing, counseling, and disclosure of suspected Alzheimer's disease and related disorders (DETeCDADRD): Executive summary of recommendations for specialty care