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Diversity of secondary metabolites from some medicinal plants and cultivated lichen mycobionts

In addition, astrocytes, which normally support neurons, become dysfunctional through a process called astrogliosis, which worsens glutamate imbalance and reduces neuronal support (Taylor et al., 2016), and genetic mutationssuch as SOD1 (causing harmful protein accumulation), FUS (interfering with RNA handling), and TBK1 or OPTN (which impair the cell's waste disposal system known as autophagy

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Moreover, the contradiction in most research outcomes vary with the source of LCPUFAs, the age and physiological status of the chickens, and genetic background (Kartikasari et al., 2012)

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