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The development of compounds with greater regional and subunit specificity would help untangle this complexity

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Unlike leucine and arginine, which directly bind to their respective sensors upstream of mTORC1 (Sestrin2 and CASTOR1), methionine is sensed indirectly through SAM (Gu et al., 2017)

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Gastrointestinal tract and gut microbiome Ingestion, together with inhalation, represents the leading route for MNPs exposure

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