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Even when all genes (not only antioxidants) in the transcriptome were considered, SOD1 had a high expression, being the gene with the 22nd highest TPM value

On the other hand, lifespan prolongation in countries with a well-developed economy is associated with an increase in patient numbers with different forms of dementia: Alzheimer, Parkinson and Huntington diseases, encephalopathy and angiopathies

Kruk PA, Rampino NJ, Bohr VA

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Fusaro M, Cianciolo G, Brandi ML, et al

With the rise of Arabidopsis as a study system, and notably genome sequencing, the pathway and its genes were characterized at the molecular genetic level, revealing (or confirming) that all four enzymes were encoded by more than one gene, thus explaining the presence of the enzyme activities in several compartments (Table 1)