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Adding these factors to the world of GH regulation radically changes the classic concept of how pituitary GH is regulated by somatostatin and GHRH, and these neurohormones by hypothalamic adrenergic pathways ( Interestingly, two of these factors, ghrelin and nesfatins, are involved in the regulation of energy homeostasis, although with opposite actions since, while ghrelin could be considered the hunger hormone, stimulating appetite, nesfatins would be the hormones of satiety, inhibiting orexigenic action of ghrelin

Gastroenterology 162 , 548561.e4 (2022)

In addition, clinical risk factors such as dyslipidemia, hypertension, and hyperglycemia should be addressed more aggressively

The mechanisms are well-characterized: angiogenesis, collagen synthesis, inflammation reduction, and neuroprotection

These natural compounds found in breast milk, along with antioxidants such as glutathione (GSH), superoxide dismutase (SOD), and lactoferrin, contribute to newborns' robust antioxidant capacity

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