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Plasma exosomal miR-122-5p from systemic lupus erythematosus patients promotes M1 polarization and worsens nephritis by suppressing FoxO3 and activating NF-B (128)
212,341 Consistent with this, transcriptomic analysis revealed that the Hedgehog signaling pathway is the most differentially activated pathway in young versus old hepatocytes after PHx, 342 which has also been verified in the context of diabetes-mediated liver disease

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The selection of embolic materials, whether they are temporary or permanent, can lead to different outcomes in terms of inducing LR (Vyas et al., 2014

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Future studies should determine whether viruses display tropism for specific cell types and cause different cellular outcomes depending on the metabolic environment and machinery present in the cells
