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This uptake of glutamate during PIDs into astrocytes by EAATs produces an increase in their [Na + ] i , a process aggravated by reduced NKA activity due to energy shortage in the hypoxic tissue (Rose and Karus, 2013)

On paper, one peptide favouring angiogenesis and cytoprotection while the other favours cell migration and actin dynamics looks complementary which is why researchers find the pairing interesting

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strongly predicts the need for mechanical ventilation

There is clear evidence of microvascular injury in the brains of deceased patients with COVID-19, including fibrinogen leakage and thinning of the endothelial cell basal laminae in the olfactory bulb 14,21

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