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Systematic review of gut microbiota and major depression

Jerlstrm-Hultqvist J, Einarsson E, Xu F et al (2013) Hydrogenosomes in the diplomonad Spironucleus salmonicida

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Various pieces of literature have found that alpha-synuclein undergoes pathological aggregation in PD, forming insoluble fibrils

Lastly, blocking GPX4 abolishes the antidepressant effects of EDA, confirming the regulatory role of the Sirt1/Nrf2/HO-1/GPX4 signaling pathway in ferroptosis, with GPX4 serving as a crucial component in the treatment of depression and anxiety via ferroptosis mechanisms (Dang et al., 2022)

Zinc is necessary for many physiological functions including insulin production, storage, and action