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In fact, mice continuously expressing MLCK are more susceptible to experimental colitis [157]

[DOI] [PubMed] [Google Scholar] 63.Bruton JD, Place N, Yamada T, Silva JP, Andrade FH, Dahlstedt AJ, Zhang SJ, Katz A, Larsson NG, Westerblad H
J.GoodmanS

In addition to intestinal diseases, tight junction disruption was also reported to be associated with other diseases that arise along the GI tubes, including GERD, Barretts esophagus, esophageal adenocarcinoma, and H

Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics
