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Antidiabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait

To elucidate the mechanism underlying the superior binding, inflamed HUVECs were pre-treated with free anti-vWF antibody for 30 min prior to PLT incubation to block the vWF binding site, resulting in a significant reduction in PLT adhesion

Several amino acids that contain a good leaving group in the -position undergo a nonenzymatic ,-elimination reaction when converted to the corresponding -keto acid by an aminotransferase or l-amino acid oxidase (Hollander et al., 1989 and references quoted therein)

Concomitantly with the development of resistance the up-regulation of a hydrogen-peroxide inducible GST was observed that might contribute to the elimination of cytotoxic reactive metabolites containing an electrophilic moiety (Shibu et al., 2012)

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