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It is produced by a mitochondrial gene, and it has been shown to play a key role in signaling and energy productionrestores homeostasis by initiating catabolic process for ATP production decreases insulin resistance[and] increases athletic performance (Seeds, 2020)

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Since the seed region is relatively short, one miRNA is able to regulate hundreds of different genes [34]

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This is exactly why the REDEFINE 4 trial exists