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When an ischemic stroke occurs, the lack of blood and glucose leads to insufficient energy supply, causing the death of neurons in the infarcted brain area

In cold hemolysis, IgM autoantibodies (cold agglutinins) bind red blood cells at lower temperatures (0 to 4C [32 to 39.2F])

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There's no rebound effect or withdrawal period

T cells isolated from RA patients are distinctly low in succinate, due to repression of the SUCLG2 gene, which brings the TCA to a halt and shifts from the oxidative to the reductive direction

doi: 10.1136/jitc-2022-005141 117 ChesneyJARibasALongGVKirkwoodJMDummerRPuzanovIet al