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Description
Wat et al

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The authors attribute the positive results to the increase in SOD in the mouse brain, relating this substance to the potential against OS [151]

In this study, a significant decrease in cell viability after XPF knockdown, which also reduces ERCC1 levels, was observed in the most resistant tumor cell line, confirming that DNA repair has a fundamental role in cisplatin resistance and variation in the protein levels of XPF and ERCC1 can explain, at least partially, the acquired resistance in tumors when compared to a normal fibroblast

Abstract Advances in the field of redox biology have contributed to the understanding of the complexity of the thiol-based system in mediating signal transduction

Further studies understanding this sexual dimorphism of MOTS-c will extend our understanding of its biology
