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doi: 10.1016/j.canlet.2025.217697 104 CostaIBarbosaDJBenfeitoSSilvaVChavarriaDBorgesFet al

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Drug Interactions CYP450 Enzyme Interactions CYP2C9 inhibition: Milk thistle may inhibit CYP2C9, which metabolizes several important medications including warfarin, amitriptyline, diazepam, and verapamil [1]

In addition, cysteine inhibits the expression of the gene encoding cystathionine -synthase

Figure 2 2.8 Statistical analyses 2.8.1 Effect of age and cognitive performance on GSH concentrations A mixed GLM model (repeated measures) was conducted to address differences in GSH according to Age group (YA vs