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Its induction has been linked to different oxidant agents such as the cancer chemoprotective agent, 3H-1,2-dimethiole-3-thione,147 alcohol,165 teributylhydroquinone,160 acetaminophen159 and bile salts.166 Activation of Nrf2 leads to the transcription of genes that codify phase II enzymes and hepatic transporters

Another study confirmed the effect on rabbits (9)

If you're using retinoids or AHA/BHA products, consider alternating days initially

This patient's stable vital signs and localized, rapid destruction of the allograft make an allergic reaction to the perfusate unlikely