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Finally, secondary antibodies conjugated with horseradish peroxidase were applied to the membrane

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The ERK pathway exerts anti-apoptotic effects by inhibiting Bim and upregulating Bcl-2 expression, whereas the JNK/p38 pathway initiates apoptosis by activating Bim, Bad, and Bax

J Clin Endocrinol Metab (1988) 66:2424

These findings suggest that natural compounds may represent a promising adjunctive strategy to address the limitations of current monotherapies and support a more holistic, longterm approach to PD management [13, 14, 15, 16, 17]

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