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642 Astrocytes obtained form stem cells isolated from patients with PD linked to LRRK2/dardarin mutation showed prominent morphological atrophy, 113 as well as decreased expression of glutamate transporters, 643 and prominent mitochondrial deficiencies

Anemia, a treatable condition, prolonged treatment can be detrimental Childhood anemia can be asymptomatic or have only minor symptoms

E.ArvanitakisZ.Macauley-RambachS

29 GST serves as a general S -glutathionylase enzyme and promotes S -glutathionylation

The study is registered at PROSPERO with ID CRD420250655809

Recent data also suggest that hydroxyurea may upregulate GPx-1 expression in several cell lines and in circulating erythrocytes, in part, by a p53-dependent pathway, providing evidence that p53-mechanisms modulate GPx-1 expression in vivo (68)