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We also noted an increase in the integrated stress response genes Atf5 and Dele1 and several CI subunits

Safety and Side Effects AOD-9604 is generally well tolerated, with a strong safety profile
Fraser, B

10.1016/j.phrs.2021.105444 36 HuangJ.ZhangC.ZhanF.ZhangJ

To further confirm that a 48 h exposure to micromolar levels of FA is not lethally genotoxic for cells proficient in DNA repair, we addressed genome instability by direct visualization of single chromosome damage in HCT116 cells (Fig

B., De Stefani, D., Rizzuto, R., Iino, M., Molkentin, J
