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Description
Elevated ROS levels disrupt antioxidant defenses, including glutathione peroxidase 4 (GPX4) activity and the cystine/glutamate antiporter system (xCT), thereby disturbing redox homeostasis and promoting lipid peroxidation and ferroptosis-related cellular damage

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Gong, J., Mou, T., Wu, H

Nikitin EA, Malakho SG, Biderman BV, Baranova AV, Lorie YY, Shevelev AY, et al

Effect of thiol modification on brain mitochondrial complex I activity
