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Cu 2+ , which released from decomposed CCF in an acidic environment, triggered GSH exhaustion (Figure 5A) and Cu + -mediated Fenton-like reaction, avoiding the potential OH elimination

It has no established upper tolerable intake limit

To date there have been a total of 8 probands reported with GCS deficiency and hemolysis

These autonomic abnormalities are closely associated with core ASD symptoms, including deficits in social interaction and language impairments (Villar de Araujo et al., 2023)

Epigenetics 7 , 635651 (2012)

However, these GnRH antagonists are still associated with side effects including reduction in bone mineral density and risk of developing osteopenia and osteoporosis due to their induction of a hypoestrogenic state which limits their treatment regime duration (Rzewuska et al., 2023)