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However, challenges such as determining the appropriate dosage, prohibitive cost, and the limited availability of quality saffron need to be addressed

Specifically, rapamycin, a representative mTOR inhibitor, significantly inhibits IL-2-mediated T-cell proliferation by blocking the cell cycle transition from the G1 phase to the S phase, thereby attenuating excessive immune responses, especially in AIDs and transplant rejection (220222)

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PARP1 spots and binds to DNA strand breaks once activated