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This mechanism is implicated in diseases such as rheumatoid arthritis (RA), where oxidative modifications of proteins in the synovial fluid contribute to the autoimmune response [127, 128]

However, accumulating evidence reveals a more complex paradigm in which GSH can also act as a chemically active participant that facilitates lethal biochemical reactions, particularly in metal-dependent contexts

TB-500 has shown similar anti-inflammatory abilities in animal models
