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The WADA and USADA have banned this substance in sports, namely due to the risks it poses to humans considering there is insufficient research

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Think of it like having a backup plan for every lead

Moderate to Severe Deficiency: For moderate to severe deficiencies, the dosage may increase to 1,000 mcg several times a week initially, followed by a maintenance dose

FEBS Journal

However, clinical trials have shown almost 15% average weight loss (12.4% more than placebo)