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Comprehensive biochemical testing demonstrates that 5 amino 1mq does not inhibit structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA methyltransferase 1 (DNMT1), or protein arginine methyltransferase 3 (PRMT3)
6), a daphnane diterpenoid isolated from a medicinal plant, was able to suppress the expression of NNMT mRNA in lung cancer cell lines to reduce tumor growth
