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Gadodiamide, for example, is a linear and thus less stable Gd chelate

Biochem Biophys Res Commun 282:321328 Roberts DW, Pumford NR, Potter DW, Benson RW, Hinson JA (1987) A sensitive immunochemical assay for acetaminophen-protein adducts

TML is then hydroxylated by 6-N-trimethyllysine dioxygenase (TMLD), which is located in the mitochondrial matrix, to form 3-hydroxy-6-N-trimethyllysine (HTML)

Two practical consequences fall out of this mechanism, and both explain the shape of the protocol below

And decreases at any age when youre under stress

doi: 10.11138/FNeur/2013.28.2.107 [DOI] [PMC free article] [PubMed] [Google Scholar] 149.Checkoway H, Powers K, Smith-Weller T, Franklin GM, Longstreth WT, Jr, Swanson PD