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doi: 10.1007/BF03402014 27

doi: 10.1038/ncomms9332

Knockout of c-Fos in hepatocytes protects the liver against HCC initiation, while overexpression of c-Fos in the liver accelerates the malignant transformation of HCC, as manifested by necrotic foci, accumulated CD45 + cells, reduced NK and B cells, increased circulating leukocytes, infiltration of immune cells and accumulated lesions in hepatocytes

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