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This demyelination process underlies subacute combined degeneration

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Very high doses of B12 taken orally may occasionally cause mild gastrointestinal disturbance in some individuals, though this is uncommon

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Moreover, elevated plasma Hcy levels have been significantly associated with hypertension (Van Guldener et al., 2003), particularly with systolic blood pressure (SBP) (Shi et al., 2019)

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A blood test is used to diagnose vitamin B12 deficiency

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