glutathione s transferase oxidative stress Early After Hematopoietic Stem Cell Transplant Glutathione, oxidative stress and neurodegeneration

E-mail: [email protected] Date of Received: 28-12-2010 Date of Accepted: 06-06-2011 Available Online: 15-08-2011 Abstract The primary role of glutathione transferase is to defend an organism from toxicities through catalyzing the reaction of glutathione (GSH) with potentially toxic compounds or metabolites to their chemically and biologically inert conju-gates

Specifically, it has been shown that the function of the gut-associated immune system is impaired in elderly humans [67, 69, 73, 74]

Exposure to heavy metals such as mercury, cadmium, lead, or arsenic can also lead to glutathione depletion

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Zhang M, Atkinson RL, Rosen JM

Dieterich, L