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immune dysregulation has been linked to ME/CFS patients (201, 255) ( Table 2 ) ( Figure 11 ), it is possible that infectious organisms result in chronic symptoms by interfering with host gene expression, immunity, and metabolism (294, 486)
This approach centers on active patient engagement through structured education and prescribed physical activity, forming the essential dual pillars of firstline care
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doi: 10.1038/s41586-020-2094-2 131 MiedaT.YabutaY.RapoluM.MotokiT.TakedaT.YoshimuraK.et al
