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Simultaneously, it suppresses glucagon secretion from pancreatic alpha cells, reducing hepatic glucose production

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GLP-1, a hormone primarily secreted from the ileum in response to nutrient intake, exerts multiple metabolic effects including appetite suppression, delayed gastric emptying, enhanced insulin secretion, and inhibition of glucagon release [4]

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What could accelerate or delay this timeline Priority review: If FDA grants priority review status, the timeline shrinks from 10 months to 6 months

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arXiv preprint arXiv:2210.04597 (2022)

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