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Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of Apoe / mice

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Span, sample size, and expression are provided in Supplementary Tables S2, S5, and S6

Meanwhile, hyperglycemia and overproduction of AGEs in both T1DM and T2DM impair collagen synthesis, produce abnormal collagen alignment and fibril size, and increase glycated collagen, thereby resulting in matrix failure and poor bone mechanical properties

Copper toxicity: A theoretical concern given the copper content