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Role of the Mitochondrial Protein Import Machinery and Protein Processing in Heart Disease

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Phase 1 study of edasalonexent (CAT-1004), an oral NF-kappaB inhibitor, in pediatric patients with Duchenne muscular dystrophy

Without enough glutathione, these reactive intermediates can sit in the liver and cause oxidative stressan imbalance between free radicals and antioxidants that can lead to cellular damage