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X., Zhang Y., Huang X

Cells resuspended in the growth medium (GM, DMEM containing 10% fetal bovine serum (FBS, Life Technologies) and 1% anti-anti), and the single cells were seeded in a cell culture flask

Phosphorylation of Nrf2 at Ser40 by Protein Kinase C in Response to Antioxidants Leads to the Release of Nrf2 from INrf2, but Is Not Required for Nrf2 Stabilization/Accumulation in the Nucleus and Transcriptional Activation of Antioxidant Response Element-mediated NAD(P)H:Quinone Oxidoreductase-1 Gene Expression

50 Joint scRNA-seq and scATAC-seq mapping further captured dynamic changes in gene regulatory networks and chromatin accessibility during aging

In addition, JHU083, an inhibitor of glutamine metabolism, has been observed to increase CD8 T cell and CD4 Th1 cell infiltration, thereby enhancing the efficacy of PD-1 blockers

It activates telomerase, the enzyme that maintains telomere length