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By enhancing levels of dopamine, norepinephrine, and serotonin, tesofensine appears to suppress appetite and elevate mood, which may help mitigate some of the underlying drivers of stimulant misuse

Additionally, the peptide's proposed anti-inflammatory properties (via modulation of TNF- and IL-6 in adipose tissue) and potential stimulation of chondrocyte metabolism offered biological plausibility for OA treatment

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