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Either GGT1 or GGT5 hydrolytically removes the -glutamyl group of LTC4 in the extracellular milieu, which results in LTD4

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denticola has evolved to assemble a similar apparatus to secrete and deliver its virulence factors such as TDE0362

The form for the fourth term was chosen because the data in [27] indicate that at normal cysteine concentrations (approximately 200 M) most of the flux away from cysteine is toward GSH and only a moderate amount towards other pathways

GBM cells reportedly develop treatment resistance through various mechanisms, including enhanced antioxidant defenses, compromised DNA repair pathways, and inhibition of apoptosis [17,18]