glutathione peroxidase antioxidant.pdf Figure 3 from Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities The Selenoprotein Glutathione Peroxidase 4:

Here are some of the potential side effects of glutathione in case of a dose larger than 5 grams: Weight gain Nausea Skin rashes, hives, or allergic reactions Eye disorders Diarrhoea Pain/Numbness Aggravated Asthma Hair whitening or loss Liver, renal, and nerve system toxic effects

Oxidative stress and aging: is methylglyoxal the hidden enemy

The schematic is illustrative and does not imply exhaustive coverage of all potential targets or agents.)

A Novel Anti-inflammatory and Pro-resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

doi: 10.1186/s40364-019-0174-y

Thus, allosteric efficacy is not a function of pocket chemistry