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De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation

In a subsequent study conducted to understand the effect of zinc on -synuclein fibrillation, the metal ion was found to decrease the lag time of aggregation (t lag ) with a simultaneous increase in apparent rate constant (k app )

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The UPRmt preserves mitochondrial import to extend lifespan

The hepatic tumor cells can activate the Wnt/-catenin signaling pathway by a paracrine function to stimulate M2 macrophage polarization, which promotes protumor activity 25
