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those results however have not been replicated in humans

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Comparing Sleep Outcomes Across GLP-1 Formulations Compounded semaglutide injections and oral versions work through identical mechanisms but differ slightly in absorption timing, which can subtly affect sleep patterns

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The discrepancy was reduced when restricting to the 195 participants with both survey and EHR data, but remained significant (self-report = 14.14% versus 8.43% in EHR, P = 1.1 10 9 paired t -test

In animal experiments involving shrews (which are able to vomit), GLP-1RAs elicit frequent episodes of vomiting, while GIPRAs do not
