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Mechanistically, luteolin engages multiple molecular networks, including the Nrf2/ARE antioxidant axis, NF-B/MAPK inflammatory cascades, PI3K/AKT/PTEN metabolic-survival pathway, TGF-/Smad fibrotic signaling, and estrogen (ER) and progesterone (PR) receptor-mediated hormonal regulation (Thiruvengadam et al., 2021

Wang Q, Wong C-H, Chan HE, Lee W-Y, Zuo Z

Montuori et al

Despite the tendency towards apoptosis, Ito et al

It consistently modulates common pathological processes including oxidative stress, inflammation, fibrosis, metabolic dysfunction, abnormal apoptosis, and hormonal imbalance (Huang and Zhang, 2021

Poor moisture control can cause clumping, weight variation, and shorter shelf-life perception