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[9] Beta-carotene, meanwhile, did not provide any protection against heart disease or stroke, as demonstrated by the Physicians Health Study

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[DOI] [PubMed] [Google Scholar] Berlin 1968 Berlin H, Berlin R, Brante G

This leads to ferritin degradation, increased labile iron release, elevated lipid peroxidation, and disruption of neuronal membrane integrity

Similarly, dietary EPA supplementation (20% of total fatty acids consumed daily for ten days) protected skin from UVB-induced immunosuppression but increased lipid peroxidation and reduced vitamin C and glutathione levels in mouse epidermis (53)

[DOI] [PMC free article] [PubMed] [Google Scholar] Noctor G., Gomez L., Vanacker H., Foyer C.H