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The decentralized clinical trial (DCT) model is an advancement in the clinical trial design, as well as a support and a development of the CNS trials challenges

Nevertheless, elevated ROS production in fast-proliferating neuroblastoma cells with high MYCN poses a threat to these cells when cyst(e)ine and/or selenocysteine are limiting and ferroptosis-triggering mechanisms are not suffciently counteracted

doi: 10.1097/01.mib.0000441201.10454.06 177 VeltkampCAnstaettMWahlKMllerSGanglSBachmannOet al
