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The recommended starting dose is 50mg and should be adapted according to the patients response and adverse effects [393]

In addition, testosterone deprivation downregulates the protein levels of MFN2 and OPA1 in obese rats, and mRNA levels of Opa1 and Mfn2 in the tibialis anterior muscle of mice, as well as upregulates DRP1 expression levels (108)

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Su principal funcin fisiolgica es ayudar a transportar los cidos grasos de cadena larga a las mitocondrias, donde pueden oxidarse para producir energa
