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doi:10.1161/CIRCULATIONAHA.116.027011 Shea MK, O'Donnell CJ, Hoffmann U, et al
Medicina (Kaunas) 2019;56 doi: 10.3390/medicina56010011

Dysbiosis in CKD has been touted to be due to slow intestinal transit time, delivery of undigested protein to the colon, decreased dietary fiber intake, iron therapy, frequent use of proton pump inhibitors and antibiotics [43]

A recent study suggested that plasma levels of 5-MT, a compound related to serotonin metabolism, may be decreased in CFS patients, but this has been interpreted as a confounder caused by serotonin-selective reuptake inhibitor (SSRI) use in these patients (40)

According to different national studies, summarized by Ahmad and Odin (2017), DILI incidence varies from 2 to 19 cases per 100,000 per year

the overall average weight by age and sex was 84.1 kg 1.1 kg
