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Clin Pharmacol Ther 2001 Feb

Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, et al

TG neurons display high expression of Nav1.7 channels (tetrodotoxin-sensitive), which lower the activation threshold and facilitate high-frequency firing
Weight of evidence: Overall evidence is LowModerate : robust mechanistic plausibility and diverse preclinical benefits

10.1212/01.wnl.0000318283.42961.e9 Neurology 117 RomanelloV.SandriM

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