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The International Journal of Neuroscience 71 (14): 9399

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27 Subsequent structural optimization of 4 led to the identification of JBSNF-000265 ( 5 ) with an IC 50 value of 0.58 0.07 M, displaying a 3-fold improvement in activity with a favorable pharmacokinetic profile

The key takeaway is that GHK-CU produces measurable, documented improvements when used consistently at appropriate doses

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