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Description
AOD 9604 in Obesity and Metabolic Research Short-Term Weight-Loss Trials AOD 9604 was advanced into human trials as an oral anti-obesity candidate

Its main mechanistic outcomes are

Studies in mice confirmed that animals lacking beta-3 receptors showed no response to AOD-9604, proving this pathway is essential to the mechanism
Both ADPR and cADPR have second messenger signaling roles [38-40, 51, 58, 60]

10.1093/carcin/bgx137 [DOI] [PMC free article] [PubMed] [Google Scholar] 67.Mottahedeh J, Haffner MC, Grogan TR, Hashimoto T, Crowell PD, Beltran H, et al

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